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KMID : 0043319840070010041
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Archives of Pharmacal Research
1984 Volume.7 No. 1 p.41 ~ p.45
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Effects of Red Ginseng-Crude Saponin on Plasma Lipid Levels in Rats Fed on a Diet High in Cholesterol and Triglyceride
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Moon CK
Kang NY/Yun YP/Lee SH/Lee HA/Kang TL
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Abstract
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The effect of Red ginseng saponin on plasma lipid levels in Wistar rats fed on a diet high in cholesterol and triglyceride was determined. A dose of Red ginseng-crude saponin (150mg/kg/day) was administered orally for 4 weeks to Wistar rats fed on a diet containing 2% cholesterol and 10% olive oil. Plasma levels of total cholesterol, HDL-cholesterol and triglyceride were measured and lipoproteins were analyzed by using electrophoretic technique. Red ginseng saponin showed no significant changes of HDL-cbolesterol level but it lowered plasma levels of total cholesterol and elevate those of triglyceride intensively.
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